The only FDA-Approved treatment for Lysosomal Acid Lipase Deficiency (LAL-D)

KANUMA® (sebelipase alfa) is a prescription medication used to treat people with a diagnosis of LAL-D.

Kanuma® (sebelipase alfa) is administered via infusion

KANUMA is indicated for the treatment of people with a diagnosis of LAL-D and is administered as an infusion by a healthcare professional.

For more information on KANUMA infusions:

Download Infusion Brochure

Getting Started on Kanuma

KANUMA is indicated for the treatment of patients with a diagnosis of LAL-D. Once your doctor has determined that KANUMA is right for you, sign up for OneSource™, a personalized patient support program from Alexion Pharmaceuticals.

There are 2 ways to get access to OneSource:

Call 1-888-765-4747

Get in touch with a OneSource Case Manager.

Download the OneSource enrollment form below

Print this form, sign it, and submit it to OneSource. Someone will be in touch within the next business day.

Submit via email:

Submit via fax:1-800-420-5150

Download OneSource enrollment form

KANUMA support by OneSource

With our experience and resources, we’re here to help you feel supported every step of the way. Here’s an overview of the services we offer.


When you have questions about LAL-D or KANUMA, we’ll work to find the answers. At OneSource, your dedicated Case Manager can provide you with:

  • Educational materials to help you learn more about LAL-D
  • Details about KANUMA
  • Information about the treatment process

Health Insurance Navigation

Health insurance can be complicated. We’re here to help make sense of it all. Your Case Manager can help by:

  • Providing information that explains your insurance coverage for KANUMA
  • Addressing financial concerns or gaps in coverage
  • Informing you of infusion centers or other treatment location options nearby

Community Connections

With OneSource by your side, you’ll never have to go it alone. Connect with others in the rare disease community who understand your experience. Your Case Manager can share information about:

  • In-person and online meetings and events specific to your condition
  • Support and resources
  • Advocacy groups
  • A peer-to-peer program called Peer Connects

Ongoing Support

When life takes a turn, OneSource is ready to keep you on track. Your Case Manager is ready to help:

  • Guide you through insurance changes or finding new treatment locations
  • Navigate your treatment through life events, such as getting married, starting a new job, moving, or traveling
  • Work with your healthcare provider and specialty pharmacy to ensure you keep receiving your medicine as prescribed

Co Pay Program

Here are some additional services we provide to help support you with KANUMA

Financial Assistance

We can provide information about resources available that may be able to help cover the costs for KANUMA.

If you have Medicare, Medicaid, or another federal- or state-funded insurance plan, we can connect you to third-party resources that may be able to help with financial assistance.

If you have commercial insurance, you may be eligible for the Alexion OneSource CoPay Program, which may be able to help cover some out-of-pocket treatment costs.

To be eligible for the CoPay Program, you must:

  • Be signed up for patient services through OneSource
  • Have commercial insurance (not part of a federal- or state-funded healthcare program)
  • Be prescribed KANUMA for an FDA-approved indication
  • Reside in the United States or its territories

Talk to your healthcare provider or OneSource Case Manager for more information about financial assistance.

Get connected with your


Case Manager


Monday through Friday,

8:30 AM to 8:00 PM (ET) or visit the website at