The only FDA-approved treatment for patients with Lysosomal Acid Lipase Deficiency (LAL-D)1

KANUMA® (sebelipase alfa) is a hydrolytic lysosomal cholesteryl ester and triacylglycerol–specific enzyme indicated for the treatment of patients with a diagnosis of LAL-D.1


KANUMA is administered as an intravenous infusion under the supervision of a healthcare professional.1 For more information, download the full Prescribing Information and Dosing and Administration brochure below:

Download Full Prescribing Information

Download Dosing And Administration Brochure

Getting Started on Kanuma® (sebelipase alfa)

KANUMA is approved by the U.S. Food and Drug Administration as a treatment for patients with a diagnosis of LAL-D.1

Here’s how OneSource™ can help you get your patients with LAL-D started on KANUMA:

Call the OneSource team at 1-888-765-4747. OneSource Customer Operations will work to facilitate order processing and delivery.

Ask your patient to sign the OneSource enrollment form to start working with a nurse case manager.

Download patient consent form

We’re Here to Help

Once you have decided that KANUMA® is right for your patient, OneSource is here to help. After your patient signs up, they will be matched with a dedicated Alexion nurse case manager who can help answer any questions about KANUMA or LAL-D.

OneSource is staffed by nurse case managers who provide one-to-one education, assistance with funding options and access to KANUMA, as well as ongoing treatment support for your patients living with LAL-D, and their caregivers.

Our Nurse Case Managers provide personalized support:

  • Assistance from a dedicated nurse case manager
  • Answers to questions about LAL-D or KANUMA
  • Resources and education on the infusion process
  • Help connecting patients with other families affected by LAL-D

The Alexion Commercial Co-pay Program can limit out-of-pocket expenses to $5 for eligible patients with commercial insurance

OneSource nurse case managers can also help navigate the insurance approval process for benefits investigation and coverage

Help get your patient connected

with their OneSource

nurse case manager


Monday through Friday,

8:30 AM to 5 PM (ET)

Connect with Alexion:     Medical Information